/* Drug Explorer v3 — scoped */
.dx{--ac:#FF6B00;--ac2:#C94F00;--ok:#1DB954}
.dx .xhero{padding:56px 0 30px;position:relative;overflow:hidden;background:#141414;color:#fff;border-bottom:1px solid #2a2a2a;--line:#2e2e2e;--surface:#1c1c1c;--muted:#b3ada5;--soft:#2a1a0e;--fg:#fff;--bg:#141414;--orange-ink:#FFB36B;--shadow:0 12px 30px rgba(0,0,0,.35)}
.dx .xhero::before{content:"";position:absolute;inset:0;background:radial-gradient(900px 520px at 92% -10%,rgba(255,107,0,.42),transparent 60%),radial-gradient(600px 420px at -5% 110%,rgba(255,107,0,.16),transparent 60%);pointer-events:none}
.dx .xhero::after{content:"";position:absolute;inset:0;background-image:linear-gradient(rgba(255,255,255,.045) 1px,transparent 1px),linear-gradient(90deg,rgba(255,255,255,.045) 1px,transparent 1px);background-size:60px 60px;pointer-events:none;mask-image:linear-gradient(180deg,#000 40%,transparent)}
.dx .xhero a{color:inherit}.dx .xhero .btn.ghost{color:#fff;border-color:rgba(255,255,255,.35)}
.dx .xhero .xk b{color:#fff}.dx .xhero .xk{background:rgba(255,255,255,.05);border-color:rgba(255,255,255,.12);backdrop-filter:blur(6px)}
.dx .xhero .xsearch input{background:#fff;color:#141414;border-color:#fff}.dx .xhero .xsearch .ico{color:#555}.dx .xhero .xsearch .kbd{color:#777;border-color:#ddd}.dx .xhero .xdrop{background:#fff;color:#141414;--muted:#625E58;--line:#E7E3DC;--soft:#FFF1E6;--orange-ink:#C94F00}
.dx .xhero .xshare a,.dx .xhero .xshare button{background:rgba(255,255,255,.06);border-color:rgba(255,255,255,.16);color:#fff}.dx .xhero .xshare .wa{color:#5EE3A0}.dx .xhero .xshare .li{color:#8FC4FF}
.dx .xhero .xforms span{background:rgba(255,255,255,.06);border-color:rgba(255,255,255,.16);color:#ddd}
.dx .xhero .xhead .art{background:rgba(255,255,255,.06);border-color:rgba(255,255,255,.14)}
.dx .xhero .xcrumbs{color:#b3ada5}
.dx .xhero .orbs{position:absolute;inset:0;pointer-events:none;overflow:hidden}.dx .xhero .orbs span{position:absolute;border-radius:50%;background:radial-gradient(circle at 35% 35%,rgba(255,107,0,.45),rgba(255,107,0,.06) 60%,transparent 70%);filter:blur(8px);animation:xo 16s ease-in-out infinite}
.dx .xhero .orbs span:nth-child(1){width:38vw;height:38vw;right:-10vw;top:-16vw}.dx .xhero .orbs span:nth-child(2){width:22vw;height:22vw;left:-8vw;bottom:-10vw;animation-delay:-6s}.dx .xhero .orbs span:nth-child(3){width:14vw;height:14vw;right:28vw;bottom:-8vw;animation-delay:-11s}
@keyframes xo{0%,100%{transform:translate(0,0) scale(1)}50%{transform:translate(-3%,5%) scale(1.08)}}
.dx .xhero .pills{position:absolute;inset:0;pointer-events:none}.dx .xhero .pills svg{position:absolute;width:72px;height:72px;opacity:.22;animation:xf 22s linear infinite;filter:drop-shadow(0 8px 16px rgba(0,0,0,.4))}
@keyframes xf{0%{transform:translateY(20px) rotate(0deg)}100%{transform:translateY(-120px) rotate(40deg)}}
.dx .xhero .wrap{position:relative;z-index:1}
.dx .xcrumbs{font-size:13px;color:var(--muted);margin-bottom:12px}.dx .xcrumbs a{color:inherit}
.dx .xeb{display:inline-flex;align-items:center;gap:8px;font-size:12px;letter-spacing:.16em;text-transform:uppercase;color:var(--orange-ink);font-weight:700}.dx .xeb::before{content:"";width:18px;height:2px;background:var(--ac)}
.dx h1{font-size:clamp(28px,3.8vw,46px);line-height:1.06;letter-spacing:-.02em;margin:10px 0 12px;max-width:30ch}.dx .xsub{max-width:72ch;font-size:17px;color:var(--muted);margin:0 0 18px}
.dx .xhead{display:grid;grid-template-columns:1fr auto;gap:24px;align-items:center}.dx .xcluster{position:relative;width:300px;height:220px;flex:none}.dx .xcluster svg{position:absolute;width:120px;height:120px;filter:drop-shadow(0 18px 30px rgba(0,0,0,.45));animation:xo 9s ease-in-out infinite}.dx .xcluster svg:nth-child(1){left:0;top:10px}.dx .xcluster svg:nth-child(2){left:120px;top:0;width:150px;height:150px;animation-delay:-3s}.dx .xcluster svg:nth-child(3){left:60px;top:110px;animation-delay:-6s}.dx .xcluster svg:nth-child(4){left:190px;top:120px;width:100px;height:100px;animation-delay:-1.5s}.dx .xhead .art{width:150px;height:150px;border-radius:28px;background:var(--surface);border:1px solid var(--line);box-shadow:var(--shadow);display:grid;place-items:center;padding:18px}.dx .xhead .art svg{width:100%;height:100%}
.dx .xtiles{display:grid;grid-template-columns:repeat(auto-fit,minmax(150px,1fr));gap:12px;margin:18px 0 6px}
.dx .xk{background:var(--surface);border:1px solid var(--line);border-radius:16px;padding:14px 16px;box-shadow:var(--shadow);position:relative;overflow:hidden}.dx .xk::before{content:"";position:absolute;left:0;top:0;bottom:0;width:4px;background:var(--ac)}
.dx .xk i{font-style:normal;font-size:11px;letter-spacing:.14em;text-transform:uppercase;color:var(--muted);display:block}.dx .xk b{display:block;font-family:var(--display);font-size:clamp(20px,2.2vw,26px);margin:4px 0 2px;color:var(--fg);letter-spacing:-.02em}.dx .xk span{font-size:12.5px;color:var(--muted)}
.dx .xsearch{position:relative;margin:16px 0 10px}.dx .xsearch input{width:100%;font:inherit;font-size:18px;padding:16px 56px 16px 52px;border:2px solid var(--line);border-radius:16px;background:var(--surface);color:inherit;box-shadow:var(--shadow);outline:none}.dx .xsearch input:focus{border-color:var(--ac)}
.dx .xsearch .ico{position:absolute;left:18px;top:50%;transform:translateY(-50%);width:22px;height:22px;color:var(--muted)}.dx .xsearch .kbd{position:absolute;right:16px;top:50%;transform:translateY(-50%);font-size:12px;color:var(--muted);border:1px solid var(--line);border-radius:6px;padding:2px 7px}
.dx .xdrop{position:absolute;left:0;right:0;top:calc(100% + 6px);background:var(--surface);border:1px solid var(--line);border-radius:14px;box-shadow:0 20px 50px rgba(0,0,0,.18);z-index:30;max-height:440px;overflow:auto;display:none}.dx .xdrop.on{display:block}
.dx .xdrop a{display:grid;grid-template-columns:36px 1fr auto;gap:12px;padding:10px 14px;border-top:1px solid var(--line);text-decoration:none;color:inherit;font-size:14.5px;align-items:center}.dx .xdrop a:first-child{border-top:0}.dx .xdrop a:hover,.dx .xdrop a.sel{background:var(--soft)}.dx .xdrop small{color:var(--muted)}.dx .xdrop .b{font-weight:700}.dx .xdrop svg{width:36px;height:36px}.dx .xdrop .hit{font-size:11px;letter-spacing:.06em;text-transform:uppercase;color:var(--orange-ink);margin-left:6px}
.dx .xtabs{display:flex;gap:6px;flex-wrap:wrap;border-bottom:1px solid var(--line);margin:22px 0 18px;position:sticky;top:64px;background:var(--bg);z-index:5;padding-top:6px}
.dx .xtab{border:0;background:transparent;color:var(--muted);font:inherit;font-weight:700;font-size:14.5px;padding:10px 14px;border-bottom:3px solid transparent;cursor:pointer;margin-bottom:-1px;white-space:nowrap}.dx .xtab.on{color:var(--fg);border-bottom-color:var(--ac)}.dx .xtab small{color:var(--muted);font-weight:500;margin-left:4px}
.dx .xpanel{display:none}.dx .xpanel.on{display:block}
.dx .xchips{display:flex;gap:8px;flex-wrap:wrap;margin:6px 0 14px}.dx .xchip{border:1px solid var(--line);background:var(--surface);color:inherit;border-radius:999px;padding:7px 13px;font:inherit;font-size:13px;cursor:pointer;text-decoration:none;display:inline-flex;align-items:center;gap:6px}.dx .xchip.on{background:var(--fg);color:var(--bg);border-color:var(--fg)}.dx .xchip small{color:var(--muted)}.dx .xchip.on small{color:inherit;opacity:.7}.dx .xchip svg{width:18px;height:18px}
.dx .xbar{display:flex;gap:10px;align-items:center;flex-wrap:wrap;margin:0 0 12px;font-size:13.5px;color:var(--muted)}.dx .xbar select,.dx .xbar input{font:inherit;font-size:13.5px;padding:8px 10px;border:1px solid var(--line);border-radius:10px;background:var(--surface);color:inherit}
.dx .xgrid{display:grid;grid-template-columns:repeat(auto-fill,minmax(250px,1fr));gap:14px}
.dx .xc{background:var(--surface);border:1px solid var(--line);border-radius:18px;padding:16px;text-decoration:none;color:inherit;display:grid;grid-template-columns:56px 1fr;gap:12px;min-width:0;transition:transform .2s,box-shadow .2s,border-color .2s;position:relative;overflow:hidden}.dx .xc:hover{transform:translateY(-3px);box-shadow:var(--shadow);border-color:var(--ac)}
.dx .xc .art{width:56px;height:56px;border-radius:14px;background:var(--soft);display:grid;place-items:center;padding:8px}.dx .xc .art svg{width:100%;height:100%}
.dx .xc h3{margin:0;font-size:16.5px;line-height:1.25}.dx .xc .m{font-size:12.5px;color:var(--muted)}.dx .xc .f{display:flex;gap:5px;flex-wrap:wrap;margin-top:6px}.dx .xc .f span{font-size:10.5px;letter-spacing:.06em;text-transform:uppercase;border:1px solid var(--line);border-radius:999px;padding:2px 7px;color:var(--muted)}.dx .xc .f span.on{border-color:var(--ac);color:var(--orange-ink)}
.dx .xc .bb{height:6px;background:var(--line);border-radius:3px;overflow:hidden;margin-top:6px}.dx .xc .bb i{display:block;height:100%;background:var(--ac)}
.dx .xc .pr{font-family:var(--display);font-size:15px;margin-top:2px}.dx .xc .pr small{font-family:var(--body);color:var(--muted);font-weight:500}
.dx .xins{display:grid;grid-template-columns:repeat(auto-fill,minmax(280px,1fr));gap:14px}.dx .xi{background:var(--surface);border:1px solid var(--line);border-radius:18px;padding:18px;box-shadow:var(--shadow);display:flex;flex-direction:column;gap:8px}.dx .xi .eb{font-size:11px;letter-spacing:.12em;text-transform:uppercase;color:var(--orange-ink);font-weight:700}.dx .xi h3{margin:0;font-size:17px;line-height:1.3}.dx .xi .big{font-family:var(--display);font-size:34px;letter-spacing:-.02em;line-height:1}.dx .xi p{margin:0;font-size:13.5px;color:var(--muted);line-height:1.5}.dx .xi .rows{display:grid;gap:6px;margin-top:4px}.dx .xi .rows a{display:grid;grid-template-columns:1fr auto;gap:8px;text-decoration:none;color:inherit;font-size:13.5px;align-items:center}.dx .xi .rows a b{font-variant-numeric:tabular-nums;color:var(--orange-ink)}.dx .xi .rows .bar{height:5px;background:var(--line);border-radius:3px;grid-column:1/-1;overflow:hidden}.dx .xi .rows .bar i{display:block;height:100%;background:var(--ac)}
.dx .donut{width:120px;height:120px;margin:0 auto}
.dx .xcls{display:grid;grid-template-columns:repeat(auto-fill,minmax(210px,1fr));gap:10px}.dx .xcls a{display:flex;justify-content:space-between;gap:8px;align-items:center;border:1px solid var(--line);background:var(--surface);border-radius:12px;padding:12px 14px;text-decoration:none;color:inherit;font-size:14px}.dx .xcls a b{font-family:var(--display);color:var(--orange-ink)}.dx .xcls a:hover{border-color:var(--ac)}
.dx .xmk{display:grid;grid-template-columns:repeat(auto-fit,minmax(230px,1fr));gap:14px}.dx .xm{background:var(--surface);border:1px solid var(--line);border-radius:16px;padding:18px}.dx .xm h3{margin:0 0 6px;font-size:17px;display:flex;align-items:center;gap:8px}.dx .xm .fl{font-size:22px}.dx .xm p,.dx .xm li{font-size:14px;line-height:1.55;color:var(--muted);margin:0}.dx .xm ul{padding-left:18px;margin:6px 0 0}.dx .xm b{color:var(--fg)}.dx .xm.wide{grid-column:1/-1}.dx .xm.wide .xtw{max-height:560px;overflow:auto;border:1px solid var(--line);border-radius:12px}.dx .xm.wide thead th{position:sticky;top:0;background:var(--surface);z-index:1}.dx .xm.wide td,.dx .xm.wide th{font-size:13px}
.dx .xtw{overflow-x:auto;border:1px solid var(--line);border-radius:14px;background:var(--surface)}.dx table{width:100%;border-collapse:collapse;font-size:13.5px}.dx th,.dx td{text-align:left;padding:9px 10px;border-bottom:1px solid var(--line);vertical-align:top}.dx th{font-size:11px;letter-spacing:.08em;text-transform:uppercase;color:var(--muted);white-space:nowrap;position:sticky;top:0;background:var(--surface);cursor:pointer;user-select:none}.dx th.asc::after{content:" ▲";font-size:9px}.dx th.desc::after{content:" ▼";font-size:9px}.dx td.n{text-align:right;font-variant-numeric:tabular-nums;white-space:nowrap}.dx tr.lo td{background:var(--soft)}.dx td .ag{color:var(--orange-ink);text-decoration:none;font-weight:600}.dx td .fi{width:22px;height:22px;vertical-align:middle;margin-right:6px}
.dx .xpill{display:inline-block;font-size:11px;letter-spacing:.06em;text-transform:uppercase;padding:3px 9px;border-radius:999px;border:1px solid var(--line);margin:0 4px 4px 0;color:var(--muted)}.dx .xpill.on{border-color:var(--ac);color:var(--orange-ink)}
.dx .ladder{display:grid;gap:8px}.dx .ladder .r{display:grid;grid-template-columns:minmax(120px,220px) 1fr auto;gap:10px;align-items:center;font-size:13.5px}.dx .ladder .r .t{display:block;height:14px;border-radius:7px;background:linear-gradient(90deg,var(--ac),#FFB36B);min-width:3px}.dx .ladder .r.lo .t{background:linear-gradient(90deg,var(--ok),#7BE495)}.dx .ladder .r.in .t{background:linear-gradient(90deg,#2F6FED,#8DB4FF)}.dx .ladder .r .v{font-variant-numeric:tabular-nums;font-weight:700;white-space:nowrap}.dx .ladder .r small{display:block;color:var(--muted);font-size:12px}
.dx .lgrp{margin:18px 0 8px;font-weight:700;font-size:15px;display:flex;justify-content:space-between;align-items:baseline;gap:10px;flex-wrap:wrap}.dx .lgrp span{font-weight:500;color:var(--muted);font-size:13px}
.dx .xcmp{background:linear-gradient(135deg,var(--surface),var(--soft));border:1px solid var(--line);border-radius:20px;padding:22px;box-shadow:var(--shadow)}.dx .xcmp .hd{display:flex;justify-content:space-between;gap:12px;flex-wrap:wrap;align-items:baseline}.dx .xcmp .ratio{font-family:var(--display);font-size:clamp(30px,4vw,46px);letter-spacing:-.03em;color:var(--orange-ink);line-height:1}.dx .xcmp .ratio small{font-size:14px;color:var(--muted);font-family:var(--body);letter-spacing:0}
.dx .xshare{display:flex;gap:8px;flex-wrap:wrap;align-items:center;margin:14px 0 0}.dx .xshare a,.dx .xshare button{display:inline-flex;align-items:center;gap:7px;border:1px solid var(--line);background:var(--surface);color:inherit;border-radius:999px;padding:8px 14px;font:inherit;font-size:13.5px;font-weight:600;cursor:pointer;text-decoration:none}.dx .xshare a:hover,.dx .xshare button:hover{border-color:var(--ac)}.dx .xshare svg{width:16px;height:16px}.dx .xshare .wa{color:#128C7E}.dx .xshare .li{color:#0A66C2}
.dx .xreq{background:var(--surface);border:1px solid var(--line);border-radius:18px;padding:22px;margin-top:18px;box-shadow:var(--shadow)}.dx .xreq h3{margin:0 0 4px}.dx .xreq .g{display:grid;grid-template-columns:repeat(auto-fit,minmax(220px,1fr));gap:10px;margin-top:12px}.dx .xreq input,.dx .xreq select,.dx .xreq textarea{width:100%;font:inherit;font-size:15px;padding:11px 13px;border:1.5px solid var(--line);border-radius:10px;background:transparent;color:inherit}.dx .xreq textarea{min-height:80px;grid-column:1/-1}.dx .xreq .ok{display:none;margin-top:10px;color:var(--orange-ink);font-weight:700}
.dx .xsticky{position:fixed;right:18px;bottom:88px;z-index:40}.dx .xsticky a{box-shadow:0 12px 30px rgba(0,0,0,.25)}
.dx .xfaq details{border-top:1px solid var(--line);padding:12px 0}.dx .xfaq summary{font-weight:700;cursor:pointer;font-size:16px}.dx .xfaq p{margin:8px 0 0;color:var(--muted)}
.dx .xband{background:var(--fg);color:var(--bg);border-radius:18px;padding:24px;display:flex;gap:18px;align-items:center;justify-content:space-between;flex-wrap:wrap;margin-top:30px}.dx .xband b{font-family:var(--display);font-size:19px;display:block}.dx .xband .btn{background:var(--ac);color:#fff}
.dx .xdisc{font-size:12.5px;color:var(--muted);border-left:3px solid var(--ac);padding:8px 14px;margin:24px 0 0}
.dx .xnote{font-size:12.5px;color:var(--muted);margin:8px 0 0}
.dx .xh2{font-size:22px;margin:26px 0 10px;letter-spacing:-.015em}
.dx .xempty{padding:30px;text-align:center;color:var(--muted);border:1px dashed var(--line);border-radius:14px}
.dx .xmore{margin:14px auto 0;display:block}
.dx .xcount{display:inline-block;min-width:1ch}
.dx .xforms{display:flex;gap:10px;flex-wrap:wrap;margin:8px 0 0}.dx .xforms span{display:inline-flex;align-items:center;gap:6px;font-size:12.5px;color:var(--muted);border:1px solid var(--line);border-radius:999px;padding:4px 10px 4px 6px;background:var(--surface)}.dx .xforms svg{width:22px;height:22px}
@media print{.dx nav,.dx header.hero,.dx .xsticky,.dx .xreq,.dx .xband,.dx footer,.dx .xtabs,.dx .xshare,.dx .orbs,.dx .pills{display:none!important}.dx .xpanel{display:block!important}.dx .xtw{overflow:visible}}
@media(max-width:700px){.dx .xcluster{display:none}.dx .xtabs{top:56px;overflow-x:auto;flex-wrap:nowrap}.dx .ladder .r{grid-template-columns:1fr auto}.dx .ladder .r .t{grid-column:1/-1}.dx .xsticky{right:12px;bottom:84px}.dx .xsearch input{font-size:16px;padding-left:46px}.dx .xhead{grid-template-columns:1fr}.dx .xhead .art{width:96px;height:96px;border-radius:20px}}